Mary&May Spicule Retinol PDRN Cream 15g

Mary&May Spicule Retinol PDRN Cream 15g

Target fine lines, enlarged-looking pores and uneven skin texture with the Mary&May Spicule Retinol PDRN Cream, an intensive night treatment combining marine-derived micro-spicules, nano-liposome retinol and CICA PDRN.

The formula contains 2,000ppm microscopic spicules, measuring approximately 80–300μm. These naturally derived micro-structures create a temporary stimulating sensation on the skin and support the effective delivery of the formula’s active ingredients.

It is also formulated with 1,000ppm nano-liposome retinol, an encapsulated form designed to improve the stability and delivery of retinol. With consistent use, it helps improve the appearance of fine lines, uneven texture, firmness and enlarged-looking pores.

CICA PDRN, listed in the formula as Sodium DNA, works alongside Niacinamide to support a smoother, brighter and healthier-looking complexion. A barrier-supporting blend of 2% Panthenol, Ceramide NP, Sodium Hyaluronate and Allantoin helps provide hydration and comfort.

Ideal for experienced skincare users or beginners who want to introduce an advanced retinol and spicule treatment gradually into their evening routine.

Benefits

• Targets the appearance of fine lines and wrinkles

• Helps improve uneven and rough skin texture

• Visually refines enlarged-looking pores

• Supports smoother and firmer-looking skin

• Contains 2,000ppm marine-derived micro-spicules

• Contains 1,000ppm nano-liposome retinol

• Formulated with CICA PDRN and Niacinamide

• Supports a brighter, more even-looking complexion

• Contains 2% Panthenol for soothing hydration

• Includes Ceramide NP, Hyaluronic Acid and Allantoin

• Fragrance-free formula

• Dermatologically tested for skin irritation

Key Ingredients

Marine-Derived Micro-Spicules – 2,000ppm
Microscopic structures measuring approximately 80–300μm that provide a stimulating skin sensation and support the delivery of active ingredients. Each 15g container contains approximately 180,000–200,000 spicules.

Nano-Liposome Retinol – 1,000ppm
An encapsulated retinol ingredient designed for improved stability and delivery. It helps refine the appearance of fine lines, wrinkles, pores and uneven skin texture.

CICA PDRN – Sodium DNA
Supports the skin’s natural renewal process and contributes to a healthier, smoother and more resilient-looking complexion.

Niacinamide
Helps improve the appearance of dullness and uneven skin tone while supporting the skin barrier.

Panthenol – 2%
Provides soothing hydration and helps support a comfortable, healthy skin barrier.

Ceramide NP, Sodium Hyaluronate & Allantoin
Help replenish moisture, soothe the skin and reduce feelings of dryness associated with active skincare products.

Suitable For

• Fine lines and early signs of ageing
• Uneven or rough skin texture
• Enlarged-looking pores
• Loss of firmness
• Dull, tired-looking skin
• Normal, combination and oily skin
• Users looking for an intensive evening treatment
• Sensitive, very dry or retinol-inexperienced skin should introduce the product particularly gradually. Do not apply it to irritated, damaged or recently exfoliated skin.

How to Use

Use during your evening skincare routine.

1. Cleanse the skin and apply a gentle, hydrating toner or serum.
2. Take a small amount of cream.
3. Apply a thin, even layer to the areas you want to target.
4. Gently press the product into the skin. Do not rub or massage aggressively.
5. Follow with a simple moisturiser if additional hydration is required.
6. For first-time use, begin one or two evenings per week. Gradually increase to two or three evenings per week according to your skin’s tolerance.

A mild prickling or tingling sensation can occur due to the micro-spicules. This sensation may also be noticeable when touching the skin after application. Discontinue use if you experience persistent burning, swelling or significant irritation.

Always apply broad-spectrum sunscreen with SPF30 or higher the following morning.

Important Precautions

• Use only during the evening.
• Do not apply on broken skin.
• Avoid facial scrubs, cleansing brushes and skincare devices on the same evening.
• Do not combine in the same routine with other retinoids, AHA, BHA, PHA, peeling products, benzoyl peroxide or strong pure Vitamin C.
  
• Do not use immediately after shaving or dermaplaning.
• Consult your doctor before using retinoid products during pregnancy or breastfeeding.
• Patch-test before first use.
• Do not overapply more product does not provide faster results.

Frequently Asked Questions

What does the Mary&May Spicule Retinol PDRN Cream target?

It is designed to improve the appearance of fine lines, enlarged-looking pores, uneven texture, dullness and reduced firmness.

What are spicules?

Spicules are naturally derived microscopic structures that create a temporary stimulating sensation and support the delivery of the formula’s active ingredients. This cream contains 2,000ppm marine-derived micro-spicules.

Does the cream feel prickly?

A mild prickling or tingling sensation is expected because of the spicules. The sensation may also be noticeable when touching the skin after application. Strong burning, swelling or persistent discomfort is not considered normal.

How much retinol does it contain?

The formula contains 1,000ppm of nano-liposome retinol. This refers to the encapsulated retinol ingredient rather than necessarily 0.1% pure retinol.

What type of PDRN does it contain?

The formula contains CICA PDRN, listed in the ingredient list as Sodium DNA. It should not be advertised as salmon PDRN.

Is it suitable for retinol beginners?

Beginners can introduce it cautiously, starting once or twice weekly. Because it combines retinol with micro-spicules, it should not be treated like a basic everyday moisturiser.

Can it be applied every night?

Daily use is not recommended initially. Begin once or twice per week and increase gradually only if the skin remains comfortable.

Can it be applied over the entire face?

Mary&May instructs users to apply an appropriate amount evenly to the face. However, beginners or sensitive skin types may prefer to begin with a thin layer only on selected areas, avoiding the eyes, lips and irritated skin.

Can I use a moisturiser afterwards?

Yes. A simple, fragrance-free moisturiser can be applied afterwards if the skin requires additional hydration. Apply it gently without excessive rubbing.

What products should not be combined with it?

Avoid using it in the same routine as other retinoids, exfoliating acids such as AHA, BHA or PHA, peeling products, benzoyl peroxide, facial scrubs or strong pure Vitamin C formulas.

Can I use a skincare device with it?

It is best to avoid microneedling tools, cleansing brushes, high-intensity facial devices and treatments that increase product penetration on the same evening.

Do I need sunscreen the following morning?

Yes. Apply a broad-spectrum sunscreen with SPF30 or higher every morning and reapply during prolonged sun exposure.

Can it be used during pregnancy or breastfeeding?

Consult your doctor before using any retinol or retinoid product during pregnancy or breastfeeding.

Is it suitable for sensitive skin?

The formula contains Panthenol, Ceramide NP, Hyaluronic Acid and Allantoin and has completed a skin irritation test. Nevertheless, retinol and spicules may still irritate reactive skin, so patch-testing and gradual use are essential.

Ingredients

Aqua (Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii (Shea) Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus (Sunflower) Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl P-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA.

Ingredients may occasionally be updated by the manufacturer. Please refer to the product packaging for the most accurate and current ingredient list.

Shop the Mary&May Spicule Retinol PDRN Cream 15g in Cyprus from Beauty Cave, with delivery throughout Cyprus and convenient collection in Nicosia.